ADME PGx Genotyping

Powerful and Flexible ADME Mutation Profiling Tool

The iPLEX^® ADME PGx panel is a powerful tool to help researchers genotype and screen for genetic variations that may influence absorption, distribution, metabolism, and excretion of drugs and compounds. The iPLEX ADME PGx panel simultaneously analyzes 192 of the most biologically-relevant pharmacogenetic ADME markers in 36 genes in a single, turnkey kit that includes all assay reagents and analysis software for use on the MassARRAY system.

Biologically Relevant Data

The iPLEX ADME PGx panel covers more than 99 percent of genotypes in the Pharma ADME Working Group’s core list*, an industry-academic consensus set of validated genes and a full set of functional genetic variants that may be used in drug development.

High Value Content

192 key ADME biomarkers comprised of SNP, insertions, deletions, and copy number variants, with ADME PGx software for star allele analysis.

Flexible Assay Format

Choose either 96-well or 384-well formats (12 or 48 samples per plate, respectively), or select assays through the Assay Explorer program to create targeted assay panels for the identification of relevant markers for a particular study.

Rapid Results

Analyze key ADME biomarkers in as little as one day with minimal hands-on time using the iPLEX Gold genotyping chemistry workflow.

Affordable

Leverage the fluorescent label-free or tag-free iPLEX chemistry for the highly competitive cost-per-sample available.

Proven Technology - iPLEX Gold Chemistry

Sequenom customers have developed over 400 assays for a wide variety of ADME markers, and screened thousands of human samples. Now the iPLEX ADME PGx panel, a standardized format for screening high-value mutations quickly and cost-effectively is available.

Get the complete list of iPLEX ADME PGx panel Haplotypes

*List available at  www.fda.gov/drugs/scienceresearch/researchareas/pharmacogenetics/ucm083378.htm