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Current Newsletter

  • April 2012
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iPLEX® Sample ID Plus Panel* – a rapid, cost-effective method for sample identification

Nothing is more critical to your results than ensuring you have analyzed the right sample. In addition, sample quality and quantity are essential for data interpretation. The iPLEX Sample ID Plus Panel provides a highly accurate method for sample QC, tracking, and identification.

In a single multiplexed assay, take advantage of:

  • 45 highly informative SNPs defined by the SNPforID consortium
  • 3 sex chromosome markers for gender matching
  • 3 built-in quality control markers to assess technical accuracy
  • 4 quality assessment assays for DNA quantification

Order the iPLEX Sample ID Plus Panel through Assays by Sequenom by contacting your local Business Development Manager. Find out more at www.mysequenom.com.

Assay Design Suite 1.0*—a powerful tool for somatic mutation and SNP design on the MassARRAY® System*

Assay Design Suite 1.0 (ADS 1.0) provides a robust software tool for assay design. With ADS 1.0, you’re no longer locked into pre-defined panels or long lead times for custom panel services. Follow up on the markers that are the most relevant to your research studies. Quickly confirm mutations discovered by next generation sequencing (NGS).

  • Take advantage of easy to use default parameters as a new user
  • Use pre-set design rules for somatic mutation assay design
  • Design using multiple iterations for better efficiency
  • Select high priority and/or control SNPs for better study planning
  • Add or remove SNPs based on study results

Visit www.mysequenom.com to access the ADS 1.0 tool and view online webinars.

EpiTYPER® 1.2*—software updates to improve methylation analysis

MassARRAY EpiTYPER is highly scalable and enables analysis of multiple CpGs without comprising performance. A new EpiTYPER v1.2 maintenance release offers new features to enhance the software’s performance including:

  • Recall functionality—easily rename amplicons and/or samples to reduce errors
  • Data Export—export data to a SQLite database
  • R-script compatibility—run any R script from within Analyzer for flexible data analysis
  • Sequence View—print and save information for external reporting

Login to www.mysequenom.com to get your EpiTYPER update.

Featured Article

A high throughput panel for identifying clinically-relevant mutation profiles in melanoma

The authors describe the design and validation of MelaCarta, a research use only assay panel for the detection of somatic mutations in melanoma samples on the MassARRAY® System.

  • A sensitive, cost-effective, and high throughput research use only assay for investigating 39 mutations in 20 genes
  • In design of quality controls to evaluate sample and assay performance
  • Mutations chosen from published literature, filtered by therapeutic potential, and screened for prevalence in 271 melanoma samples
  • Inclusion of BRAF, NRAS, CDK, PTK2B and other genes suspected to be involved in pathways that could be targeted with anti-cancer therapies


 

*The MassARRAY System, Assay Design Suite 1.0, EpiTYPER v1.2 software, and iPLEX Sample ID Plus Panel are For Research Use Only. Not for Use in Diagnostic Procedures.

 
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