Low Frequent Mutations

SNP Genotyping
How it Works
Literature
DNA Methylation
Molecular Typing
Rare Mutation Profiling
Gene Expression Analysis

Compared to Sequencing, MassARRAY provides a significant advantage for the detection of low frequent mutations – e.g. in admixed samples of tumor and healthy tissue

This has been demonstrated in several publications:

  • Thomas, R K, et.al. (2007) Nature Genetics Mar;39(3):347-351
  • Vivante, A et al. (2007) Leukemia; 21: 1318 - 21

Sequencing Trace & MassARRAY Spectrum