Molecular Typing with iSEQ™
Technical Information & Downloads
Today’s microbiology testing industry demands fast answers to accurately detect and type organisms. If you are tired of relying on labor intensive and subjective assessments of phenotypic traits, or expensive sequencing methods that lock you into a proprietary or inflexible database, make a move to the new standard in molecular typing.
Automated Molecular Typing
The MassARRAY® System with iSEQ™ software sets a new precedent for rapid, accurate molecular identification of microbes, viruses, and other haploid organisms. By combining the sensitivity of PCR and the accuracy of MALDI-TOF Mass Spectrometry, you can analyze one or more target regions on multiple samples in a convenient, homogeneous assay format.
Customize Your Comparative Sequence Analysis
iSEQ Comparative Sequence Analysis offers superior sensitivity and versatility- you can choose any genomic region that discriminates your strains or samples, not just 16s rDNA. Analyze bacteria one day and viruses the next, with easy and flexible assay set up. Keep up to the minute with evolving or seasonally variable strains with the open and fully customizable reference database, because you control what sequences you upload- all in simple FASTA format from any database.
Take Your Analysis to the Next Level
iSEQ gives you automated, reproducible, and rapid sample identification, but the benefits don't stop there. The software automatically calls out single base pair deviations and identifies new sequences. You can also produce distance matrices for sample clustering. Intuitive graphical and numerical interpretation tools allow you to navigate the spectra details and view the entire forward and reverse sequence of your target region.
What Are Researchers Saying about iSEQ Comparative Sequence Analysis?
"In our laboratory, we use the MassARRAY iSEQ identification system in several projects. This technology serves as a basis for developing new methods for rapid genotyping of hepatitis B and C viruses and quasispecies analysis of the hepatitis C virus. Currently, a new project is underway to adapt the MassARRAY system to sequencing of whole genomes of hepatitis A and B viruses."
Laboratory of Molecular Epidemiology and Bioinformatics, Division of Viral Hepatitis, Centers for Disease Control and Prevention (CDC, USA).
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