Genetic Analysis
SNP Genotyping
Applications Applications
DNA Methylation Analysis DNA Methylation Analysis
SNP Genotyping SNP Genotyping
iPLEX SNP Genotyping Overview iPLEX SNP Genotyping Overview
How it Works How it Works
Literature Literature
Reagents Reagents
Molecular Typing Molecular Typing
Rare Mutation Profiling Rare Mutation Profiling
Gene Expression Analysis Gene Expression Analysis
Research Area Research Area
Systems Systems

SNP Genotyping with iPLEX® Gold

Technical Information & Downloads
Learn how you can analyze Copy Number Variation(CNV) using the MassARRAY










Study Range - Number of SNPs versus Number of Samples
               

If blazing through SNP validation and fine-mapping studies doesn’t get you excited, then read no further because that’s what iPLEX Gold does, really well in fact. Other genotyping technologies talk a big game about their multiplexing capabilities and throughput, but when the FLASH demos are finished and the glossy brochures are tossed aside, you’re left with days of costly primer design and assay optimization.

Flex the Plex with iPLEX Gold

Now you can rapidly sift through all of the data left behind from your genome-wide association studies and sequencing experiments with iPLEX Gold. The iPLEX Gold assay on the MassARRAY® Platform provides an ideal balance of multiplexing and throughput that enables researchers to make short work of large, fine-mapping and SNP validation studies, or any routine applications that employ focused SNP panels.

The iPLEX Gold assay combines the benefits of robust single-base primer extension biochemistry with the sensitivity and accuracy of MassARRAY MALDI-TOF MS detection providing you with:


Cost-Effective SNP Validation and Fine-Mapping
Have some interesting regions you’re eager to explore after a whole genome association study or maybe it’s time to ramp up that candidate gene analysis project? There is no more cost effective approach out there than iPLEX Gold.  Simple assay design and an unlabeled oligos lay the groundwork for you to:
  • Multiplex up to 40 SNPs in a single well 
  • Process up to 384 samples in parallel
 
Trusted for SNP Validation and Fine-Mapping

iPLEX Gold is used for sub-whole genome study applications by SNP genotyping centers all over the globe. Read for yourself just how this genotyping workhorse is driving research in the world’s finest SNP genotyping labs.

Or get started today with your SNP Genotyping project through our certified service provider. Genome Quebec provides high-throughput genotyping services on a fee for services basis, and is the premier center of excellence offering fine-mapping with our MassARRAY platform.

 


Flexibility to Scale with your Project Design 

Flex the Plex when you need to switch up the SNPs under investigation with highly flexible assay design, low cost oligos, and minimal waiting time. That’s because iPLEX Gold offers you robust software design and assays that don’t require fluorescent probes, just universal PCR conditions and primer extension with your everyday oligos. 


What Are Researchers Saying About iPLEX Gold?

StaceyGabrial "Sequenom's iPLEX assay is a powerful tool for evaluating targeted sets of SNPs in a cost effective manner. Due to an efficient multiplexed assay design coupled with a robust chemistry, it is ideally suited for fine mapping and other genotyping studies using tens to hundreds of SNPs over hundreds to thousands of samples."
Stacey Gabriel, Ph.D.,
Director of the Genetic Analysis Platform
Broad Institute at Harvard University and Massachusetts Institute of Technology