Genetic Analysis
Gene Expression Analysis
Applications Applications
DNA Methylation Analysis DNA Methylation Analysis
SNP Genotyping SNP Genotyping
Molecular Typing Molecular Typing
Rare Mutation Profiling Rare Mutation Profiling
Gene Expression Analysis Gene Expression Analysis
QGE Overview QGE Overview
How it Works How it Works
Reagents Reagents
Literature Literature
Research Area Research Area
Systems Systems

QGE Overview

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QGE Overview

MassARRAY® QGE precisely measures gene expression levels from a wide variety of samples using real competitive PCR and MALDI-TOF MS. It is the ideal solution for post-array validation and multiplexed application.

  • Ideal for investigating a few or several hundred regions over multiple samples
  • >10-1,000 times greater sensitivity over real-time PCR
  • Multiplex up to 24 targets per reaction
  • High precision over a large dynamic range
  • Most comprehensive data normalization solution for accurate quantification
Applications for QGE
  • Post-array validation
  • Splice variant analysis
  • Biomarker characterization
  • Disease association studies
  • Copy number variation
  • Loss of heterozygosity
  • Viral load quantification
  • Infection resistance and drug response

 

QGE Array
 
Gene Expression Studies
  MassARRAy System  MassARRAY QGE
Provides absolute quantification for key studies such as target validation, dose response, or copy number variation
Arrow Down 
Microarray Arrow Data Analysis  Arrow Target Validation Arrow Drug Discovery
WGA & Expression Profiling   Data Analysis & Target Prioritization   Target Validation & Characterization  
Drug Efficacy Arrow

Cellsurface

Tumor 

 Arrow Drug Response  Arrow Therapeutic or Diagnostic
Drug Efficacy Studies   Tumor Classification Cell surface Expression   Dose Response or CNV Quantification