MassARRAY® Tools for Epigenomic Research
Quantitative DNA Methylation Analysis
MassARRAY® EpiTYPER precisely measures DNA methylation using bisulfite treatment, MassCLEAVE® chemistry and MALDI-TOF MS. It is the ideal solution for post-array validation or targeted gene promoter analysis.
- Ideal for investigating a few or several hundred regions over multiple samples
- Target sequences up to 600bp in one reaction enable discovery of differential methylation within large promoter regions
- Delivers individual methylation ratios for CpGs within a target sequence
- Quantitative profiling with <5% variability
- Most comprehensive and cost effective high throughput quantitative technology for DNA methylation analysis
Sequenom Standard EpiPanel
EpiTYPER technology, combined with the simplicity of the following pre-designed panels, offers rapid and quantitative methylation profiling of 41 commonly analyzed genes. The panel offers the speed and convenience of using “off the shelf” validated assays. A comparable combination of fast, inexpensive, and quantitative analysis is not available elsewhere.
EpiDesigner
If your gene(s) of interest are not included in this version of the Sequenom Standard EpiPanel, you can easily design assays for any genomic region using Sequenom’s EpiDesigner software. EpiDesigner is a tool for designing quantitative DNA methylation experiments for Sequenom’s EpiTYPER technology. This program allows simple design of primers for bisulfite treated genomic DNA and recommends primer pairs for individual assays. |